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Data processing and statistical analysis Peak areas were obtained from Tracefinder with a target compound list of compounds of interests at a window of five parts per million accuracy (see Supplementary Tables S4S6)

There is growing interest in the potential regulation of the intestinal microbiota by sex hormones

The coupling reaction was initiated by incubation at 25 C for 1 h and was followed by the addition of Apyrase (New England BioLab) to catalyze the hydrolysis of GDP overnight at 4 C

In other words, a weak methionine efflux is responsible for maintaining Hcy homeostasis in the model regardless of the availability of vitamin B 12

Conducting rigorous studies like those that established the benefits of injectable GLP-1 RAs such as tirzepatide, semaglutide, dulaglutide, and liraglutide on CKD, MASH, and cardiovascular outcomes will be crucial in determining the full clinical utility of these novel agents