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Proteasome helps to degrade oxidized, modified, or damaged proteins, thereby keeping the cellular environment functional

We suspected that rec-ECM1 was either inefficiently delivered to the liver injury site or was rapidly cleared or interacted with other proteins in circulation

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Proteins were visualized using the Supersignal West Pico Chemiluminescent Substrate system (Pierce, Fenton, MO) and molecular weights determined by comparison to protein ladders (BenchMark, Invitrogen