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It has been shown that knockdown of the GLS-1 gene in acute myeloid leukemia (AML) cell lines disrupted glutamine-driven OXPHOS, resulting in reduced cell proliferation and the induction of apoptosis (10)

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doi: 10.1016/s0891-5849(99)00131-8

Although typically considered an intracellular antioxidant with tumour-promoting capabilities 2 , glutathione (GSH), as a tripeptide of cysteine, glutamate and glycine, can be catabolized to release amino acids

Arch Dis Child Fetal Neonatal Ed 80:F59F63 Nahata MC, Powell DA, Durrell DE, Miller MA (1984) Acetaminophen accumulation in pediatric patients after repeated therapeutic doses