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Allergens or toxins in the urine are thought to cause the bladder walls to become sensitized to increased mast cells.[ref][ref][ref] Vulvodynia and mast cell activation: Vulvodynia is a chronic genital pain condition that includes an increased number of mast cells

Adequate blood supply is critical for wound healing because blood delivers oxygen, nutrients, and immune cells to damaged tissue while removing waste products and dead cells

The reaction can be expected during thermal food processing, particularly in dairy products such as heated milk, milk powder, and infant formula, containing an excess of lactose, in cereal-derived products such as biscuits and breakfast cereals, containing maltose, and in heat-treated fruits, e.g., pasteurized fruit juices, rich in fructose and glucose 555