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Nausea from tirzepatide peaks 2472 hours post-injection and typically resolves within 48 weeks at a stable dose as GLP-1 receptor density downregulates in the gut

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Owing to its low cost and simplicity, in vitro cellular experiments are routinely used to assess metel-based NP toxicity, allowing deeper investigation into molecular mechanisms

The hourly locomotor activity was further analyzed at each five-minute interval (Fig