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Concurrently, real-time clinical adjustment strategies are emerging, combining organoid-informed predictions with longitudinal monitoring toolssuch as tDNA for tracking metabolic mutation burden, and FDG-PET imaging to assess glucose metabolism [75]

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2 There is also a much-discussed link to the Wnt/-catenin pathway, which is a genuine master regulator of the hair cycle: active -catenin signaling in the dermal papilla drives follicles into anagen and enhances their hair-inducing capacity, while reduced signaling is associated with regression and miniaturization

WT- and T315I-Bcr-Abl-transformed cells are very different in replication stress, dTTP, and glutathione (GSH) levels