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Nebeling L, Miraldi F, Shurin S, Lerner E

For the mass spectrometry, the data-dependent MS 2 scan conditions were applied in both positive and negative mode: the scan range was from m/z 2501500, resolution was 60,000 for MS, and 30,000 for DDMS 2 (top 10), and the AGC target was 3E 6 for full MS and 1E 5 for DDMS 2 , allowing ions to accumulate for up to 200 ms for MS and 50 ms for MS/MS

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Most neurodegenerative diseases are characterized by the deposition of misfolded proteins (e.g., -synuclein, -amyloid, huntingtin) and degeneration of brain networks (Vaquer-Alicea and Diamond 2019)

Eur J Med Chem (2018) 153:10515