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10,11 About 20% of people with a DFU will undergo a lower extremity amputation and the 5-year mortality rate for them is greater than 70%

doi: 10.1007/s00134-015-3934-7 87

Ipamorelin acts on the distinct GHS-R1a receptor, amplifying the GH release signal through a separate intracellular pathway involving phospholipase C and protein kinase C