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Arezes, J

To tackle challenges, new approaches are underway: combining antifungal drugs, developing fungal vaccines, creating innovative medications (including small - molecule peptides and nanoparticles), extracting actives from traditional Chinese medicine, and leveraging AI for drug designall aiming to improve fungal infection management (D)

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Interestingly, the LIN28B/MYC/miR-34a-5p pathway can be therapeutically exploited: in fact, when using LIN28B inhibitors, miR-34a-5p increases and PKM2 decreases while tumor growth and lung metastasis are suppressed [42]

Peptides are naturally occurring molecules made of short chains of amino acids, typically between 2 and 50 amino acids linked together