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On the other hand, for this reducing power to arrive at GSH, the reduced S from Met must transit the metazoan Hcy Cys transsulfuration pathway, the enzymes, substrates, and products of which supply H 2 S for signaling activities

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NAPstars specifically respond to dynamic NADP redox changes in vitro To further test the dynamic and specific responsiveness of NAPstars to changes in NADP redox status, we used recombinant NAPstar probes to monitor NADP dynamics in enzyme assays in vitro (Supplementary Fig