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doi:10.1146/annurev-immunol-073119-095439 194
The actor who played Lurch in the original Addams Family series Ted Cassidy (below) had gigantism as a child (leading to his large stature) and acromegaly after puberty due to an overactive pituitary gland
BPC-157 with TB4 Recommended for recovery and healing Pros Combines two peptides that accelerate recovery from injury Stimulates collagen production to help regenerate tissues Reduces inflammation and joint pain May promote cardiovascular health Cons BPC-157 works by an as-yet undetermined mechanism of action BPC-157 presents a risk of immunogenicity and life-threatening immune responses Usually administered by subcutaneous injection Prohibited by the World Anti-Doping Agency The BPC-157 and TB4 stack accelerates tissue repair and recovery from injury
Increased PGAM5 results in the overactivation of Drp1-mediated mitochondrial fission, the accumulation of damaged mitochondria, a reduction in ATP production and an imbalance in mitochondrial dynamics 13,19
J Proteomics 126:8293 Datta R, Kumar D, Sultana A, Hazra S, Bhattacharyya D, Chattopadhyay S (2015) Glutathione regulates 1-aminocyclopropane-1-carboxylate synthase transcription via WRKY33 and 1-aminocyclopropane-1-carboxylate oxidase by modulating messenger RNA stability to induce ethylene synthesis during stress
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