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Mitochondrial-Derived Peptide Origins MOTS-c belongs to a small but growing class of peptides discovered to be encoded within mitochondrial DNA rather than nuclear DNA a finding that reshaped scientific understanding of what mitochondria are capable of producing

Bidwell LC et al (2010): Alpha-2 Adrenergic Receptors and Attention-Deficit/Hyperactivity Disorder

One widely cited paper found that it can reduce inflammatory signaling and colitis signs in KPV uptake

Sensitivity changes: Areas that have become either numb or excessively tender compared to surrounding skin may have nerve irritation

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