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Tissue-level deficiency of cobalamin is associated with an increase in the urinary and serum concentrations of an organic acid called methylmalonic acid, which is an alternative product of a cobalamin dependent pathway within the mitochondria

Intravenous B12 Administration For those with severe vitamin B12 deficiency, getting B12 through an IV is a quick and effective way to treat it

Matrix-related gene activity

Careful consideration must be taken when measuring out the appropriate amounts as too little or too much could have detrimental effects on a given products performance