[1], [2], [3], [4] A 2021 retrospective study conducted at the Institute for Hormonal Balance in Orlando, Florida, that evaluated the use of BPC 157, alone or in combination with thymosin-beta-4 (TB4), indicates in its methodology that no human clinical trials evaluating the use of BPC 157 to help with knee pain have been published (see Table 1)
Pre-surgical use could theoretically optimize tissue condition for healing
Disclaimer BPC-157 is strictly for laboratory research and not intended for human, veterinary, or household use
Written by: FormBlends Medical Team | Last reviewed: May 29, 2026 | Sources: PubMed, peer-reviewed pharmacology journals, FDA databases
Commercial copper peptide serums (skincare products) Popular brands (The Ordinary, SkinCeuticals, Drunk Elephant, etc.): Follow manufacturer instructions (usually room temp) Refrigeration after opening extends life Keep away from heat and light Bathroom storage often too warm and humid High-concentration copper peptide serums: More sensitive to degradation Refrigeration strongly recommended Watch for color changes (indicates oxidation) Low-concentration products: More stable (less copper to oxidize) Room temp usually fine Refrigeration still beneficial Copper peptide + hyaluronic acid combinations Many products combine copper peptides with hyaluronic acid