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4 hours | Primary site of action: vascular signaling pathways, NO system | Key receptors: VEGFR2, eNOS | Research focus: gastrointestinal, tendons, inflammation | Endogenous: no (synthetic, derived from gastric juice) | Gene modulation: limited documentation TB-500 Half-life: approx

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Micheroli R, Tellenbach C, Scherer A et al (2020) Effectiveness of secukinumab versus an alternative TNF inhibitor in patients with axial spondyloarthritis previously exposed to TNF inhibitors in the swiss clinical quality management cohort

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