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Although ROS are involved in the initiation, progression, and metastasis of cancer, they also exert beneficial activities, such as apoptosis by chemotherapeutic agent activation 23

These findings indicate that the localization and roles of ZIP7 and ZIP13 require further verification

Interestingly, in a study investigating the interplay between ROS and AKT signalling in Drosophila regeneration, the importance of nutrient sensing and metabolism in this pathway was highlighted 125

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The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinsons disease