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When a simple walk to the mailbox triggers days of post-exertional malaise (PEM), it becomes clear that the body's fundamental power grid is malfunctioning

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The antioxidant transcriptome is particularly relevant given the high oxidative burden in aged neural tissue

10.1038/s41569-021-00632-2 18 LiL.SuQ.WangY.DaiR.LuY.SuB.et al (2011)

The most frequent side effects are headache, increased heart rate, stomatitis, pruritus, urticaria, nausea, vomiting, abdominal pain, fever, decrease in the blood pressure, diarrhoea and noises in the ears