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This work was supported by grants from Grant-in-Aid for Scientific Research (A) (23H00354), a challenging Research (Exploratory, 23 K18072) from JSPS to HK, CONICET PIP 1982 and ANPCyT-MINCyT PICT-2018-01378

Mutations in genes encoding astrocyte-specific proteins can lead either to loss of functions with subsequent secondary neural injury or to the emergence of aberrant cellular phenotypes damaging nervous tissue in yet unidentified manner

Therefore, metabolic vulnerabilities are attacked using the synthetic lethality approach in ovarian cancer cells overexpressing xCT, rather than directly inhibiting xCT or GPX4

some studies reveal a doseresponse link, while others do not

* Group I v/s Group II Correlation between plasma GGT and MDA in alcoholics Correlation between plasma GGT and GSH in alcoholics Correlation between plasma MDA and GSH in alcoholics Discussion Gamma Glutamyl Transferase (GGT) is an enzyme which is involved in the transfer of the -glutamyl residue from the -glutamyl peptides to the amino acids