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A1-D1R Heteromers There exist antagonistic intramembrane A1-D1R interactions at the AC level in the dorsal, ventral striatum, and prefrontal cortex (59)

Similar to the latter, the enhanced version is believed to offer a spectrum of potential cognitive and neurological benefits

doi: 10.1016/j.cell.2020.02.035 240 MattSMAllenJMLawsonMAMailingLJWoodsJAJohnsonRW

Epub 2006 Feb 9

For example, a modified DNA peptide therapy targeting pro-inflammatory interleukin (IL)-17 significantly reduced organ damage and increased the survival of treated lupus-prone mice, [48] while targeting the CXC chemokine ligand 10 (CXCL10) attenuated experimental autoimmune encephalomyelitis