Unlike true peptides, Dihexa is not degraded by peptidases, has a relatively small molecular weight (~480 Da), and crosses the blood-brain barrier efficiently after systemic administration
Because it is so versatile, it is often considered a "conditionally essential" amino acid, meaning that while you usually make enough, there are many real-world scenarios where you might need an extra boost from your diet or a high-quality supplement
Most users apply a new patch daily or every other day, depending on the severity of the condition and desired recovery speed
Rational for discussing cardiorespiratory fitness, zone 2, and VO max despite having covered the topic extensively [2:30]
Furthermore, significant increase in CSF levels of glutamate and glutamine among MDD patients compared to healthy control (108) has been observed and linked to hyperactivation of NMDA receptors (109), inflammatory process (110, 111) and serotonergic signaling (111)