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However, there were no specific tools used to measure these improvements

8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years

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On the systems-level, the cerebellar nuclei outputs directly regulate movement signals in the brainstem and spinal cord, boost motor commands in the cerebral cortex via the thalamus, and modulate signals for adaptive learning through inhibitory projections to the inferior olive

Shah, R., Reyes-Gordillo, K., Cheng, Y., Varatharajalu, R., Ibrahim, J., & Lakshman, M