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The starting conformations were obtained by manually binding GS(H) to a snapshot of the MD simulation of TRaQ-G and the crystal structure of MeTRaQ-G, respectively

Critical revision of the article CS-G and JR

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This cellular damage activates hepatic stellate cells (HSCs), which are key players in liver fibrogenesis, contributing to the deposition of extracellular matrix proteins and the progression of fibrosis [8,9,10]