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Wang L, Duan W, Ruan C, Liu J, Miyagishi M, Kasim V, et al

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A systematic review published in a 2025 orthopedic sports medicine journal, covering 35 preclinical studies, confirmed that BPC-157 reduced inflammatory cytokines and improved muscle injury outcomes

10.2174/0109298665330728241025082011 186 NeaguA

As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5