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Upon activation cues, GSTO1 removes this inhibitory SSG on ASC to enable ASC speck formation and productive inflammasome assembly 68

doi: 10.1038/ncomms14063

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Mol Cancer Ther 2007

One of the primary metabolites of BPC-157 is thought to be Proline, which has been shown to play a role in superoxide production and intracellular cascades whose downstream effects could interfere with a variety of biomolecules leading to widespread pathologic effects [23, 51, 74, 75]