The wealth of preclinical data suggests it holds immense promise, and it's our job to provide the highest-quality version of this tool so that researchers can continue to push the boundaries of science and potentially uncover new ways to address debilitating conditions
It was shown that aged or/and damaged RBCs are sequestrated in the hepatic sinusoid in a PS-dependent way, and the human sinonasal epithelial cells (HSECs) mediate the recognition and the binding of damaged RBCs in a PS-dependent manner via stabilin-1 and stabilin-2 (pro-phagocytic signals and ligandligand interactions) [275,276,277]
NAFLD could be considered an hepatic manifestation of metabolic syndrome, with a strong association with obesity, type 2 diabetes, hypertension, and dyslipidaemia (3)
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