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Recent studies have begun to explore the role of the ocular surface in the lung eye axis, emphasizing the bidirectional relationship between the respiratory system and eye health, suggesting that respiratory diseases may have an impact on eye diseases ( Statements Author contributions YuY: Writingoriginal draft, Writingreview and editing, Visualization

Antibodies form against these cells and the proteins themselves, leading to inflammation

The Mechanisms Explained Understanding the mechanism is key to understanding why the results are so broad

Superoxide dismutase is the body's first line of enzymatic defense against intracellular free radical production through reduction of one-electron dismutation of oxygen (O 2 - ) to hydrogen peroxide (H 2 O 2 ) [10]

ROS generation leads to oxidation of the ASK1 inhibitor thioredoxin, separating and activating ASK1 from the inactive ASK1thioredoxin complex