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The mechanism underlying the regulation of glucose homeostasis by E2 signaling is that the ER-expressing neurons in the ventrolateral subdivision of the ventromedial hypothalamic nucleus can sense glucose fluctuations throughout the body and regulate glucose homeostasis [194]

J Vet Med Sci 79:17851790

The main mode of action of CBZ is via the inhibition of sodium channels, although it is contested 9 , since CBZ has also been shown to bind to voltage-gated calcium channels 10 , decreasing the flux of Ca +2 across the neuronal membrane, and also increase the effect of GABA 11,12

While suppression of the proatherogenic T h 1 subset may confer some protection from atherosclerosis in G6PD-d, it is necessary to determine whether the other T cell subsets, particularly the atheroprotective subsets, are similarly affected