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doi: 10.1182/blood-2006-05-026401

Senescent cells do not divide upon stimulation and often display an altered secretory profile along with increased lysosomal activity

The study was conducted on 32 male mice divided into four groups: a control (C) group receiving a standard diet with biotin, a biotin-deficient (BD) group on a biotin-free diet, a ketogenic control (KC) group on a ketogenic diet (low-carbohydrate and high-fat) with biotin, and a ketogenic biotin-deficient (KBD) group on a ketogenic diet without biotin

2023;14(4):e00573