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The Foundational Mechanism: BPC-157 as a Cytoprotective Agent Deconstructing the Gastrointestinal Repair Mechanisms Deconstructing the Neuroprotective Mechanisms Synthesis: BPC-157 as a True Gut-Brain Axis Modulator The Practitioners Dilemma: The Evidence Gap & Safety Profile Conclusion The Foundational Mechanism: BPC-157 as a Cytoprotective Agent To fully appreciate the diverse therapeutic potential of BPC-157, it is essential to first understand its fundamental role as a systemic cytoprotective agent

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Inhibition of key regulators of 2D cell locomotion such as actin polymerization, cell-matrix adhesion, and myosin contractility fail to block confined migration of MDA-MB-231 breast cancer cells [153], suggesting the existence of alternative mechanisms facilitating their movement