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While its hard to attribute its origin to a single individual or group, it was adopted as a method to bypass the gut and rapidly elevate glutathione levels, particularly for patients with Parkinsons, liver dysfunction or heavy toxic burdens, he said

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Rapid weight gain may also occur

"Toxicity of Glutathione-Binding Metals: A Review of Targets and Mechanisms"

However, this adaptive mechanism may not be sufficient to counteract the overwhelming oxidative burden caused by iron overload (83)