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Name: what's the difference between melanotan 1 and melanotan 2 Peptide — 10mg Melanotan 1 Vs Melanotan 2
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J Clin Endocrinol Metab 106(11):e4652-e4665, 2021

We measured host cell death in WT macrophages and IFN-I release in Casp1/11 -/- macrophages in the presence or absence of BSO

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It directly inhibited the stearoyl-CoA desaturase-1 (SCD1) protein to trigger ferroptosis of ovarian cancer, evidenced by the increased ROS, total iron, and Fe 2+ levels and downregulation of ferroptosis inhibitors (SLC7A11 and GPX4), thus suppressing cancer progression in the SKOV-3 xenograft model (Liu et al., 2022)