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Hepatology 2023, 77: 1866-1881

Circulating zinc levels decline during pregnancy due to haemodilution, reduced levels of zinc-binding protein, hormonal changes, and active transfer of zinc from the mother to the fetus

Finally, we discuss promising therapeutic strategies targeting this -syn-ferroptosis axis, including -syn aggregation inhibitors, iron chelators, and glia-modulating agents, highlighting their potential as disease-modifying interventions

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