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This area of research has applications in: .Tissue engineering .Regenerative biology .Biomaterials research .Wound-healing models .Vascular biology Understanding these mechanisms may help researchers develop improved experimental models for studying tissue regeneration

VEGFR2 is thought to play an important role in endothelial cell growth, proliferation, and longevity

Even more frequently, non-specific resistance mechanisms, involving modification of cell envelope charge, composition or rigidity as well as increased expression of drug resistance transporters can contribute to resistance