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The virus-induced hypoxia/Warburg effect could potentially compromise endocrinal, cardiovascular, neurocognitive, gastrointestinal, pulmonary, and reproductive functions that demand high levels of mitochondrial O 2 consumption, OXPHOS, and ATP reserve

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Ferroptosis and RF exhibit a mutually reinforcing relationship: in CKD renal tissues, lipid peroxidation, necroinflammation, and iron overload damage parenchymal cells, driving fibrotic accumulation (189)

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Inject slowly to reduce tissue trauma