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Several mechanisms have been proposed to explain the role of TH signaling in cataractogenesis: Lens Protein Dysregulation: TH deficiency may impair the synthesis and turnover of lens structural proteins, such as crystallins, leading to the accumulation of misfolded or damaged proteins, which promotes lens opacification [135]
In scientific and market-oriented settings, IGF-1-LR3 is primarily associated with research into growth factor pathways, cellular activation, and metabolic response
Downs syndrome, neuroinflammation, and Alzheimer neuropathogenesis