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The membranes were blocked in QuickBlock Blocking Buffer for 15 min (Beyotime) and then probed with primary antibodies against fibronectin, collagen I, GFAP, -SMA, TGF1, SMAD3, phospho-Smad3 (Thr8), SMAD4, -tubulin, and -actin (Supplementary Table 2)

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However, we have a preliminary result: the minimal erythemal dose of GSSG was significantly increased by its application to the UV-irradiated skin of hairless mice (data not shown)