A pharmaceutical formulation comprising: an effective amount of cagrilintide and semaglutide, more than 10% w/v and less than 22% w/v, such as 10-20% w/v cyclodextrin of the hydroxypropyl-substituted alpha and/or beta type, said cyclodextrin comprising a minimum of about 0.4 and a maximum of about 1.0 hydroxypropyls per glucose unit, such as 0.58-1 .0 hydroxypropyls per glucose unit, about 3-30 mM histidine, about 10-40 mg/ml sorbitol, up to 2.0 mg/ml, such as up to 1 .5 mg/ml polysorbate 20 and/or 80, about 75-90% w/w water and having a pH of 5.6-6.0
Am J Physiol Renal Physiol 295:F388F396 Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A et al (2013) Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1 secretion
Supplied as a lyophilized powder, Purity Base GHK-Cu is independently verified at 99.860% purity by Janoshik Independent Peptide Analytics using HPLC and Mass Spectrometry, with heavy metals reported as not detected
For this reason, regular users may want to consider supplementing with glutathione
Epithalon sold by Evolve Peptides is not intended for ingestion, injection, or topical application in humans or animals