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Clin Cancer Res 20(7):1946-54, 2014

Consequently, the GSH deprotonation step was considered non-rate-determining and thermodynamically favoured, leading us to use the GSH-thiolate as the starting point to compute the reaction mechanism for the conversion of flav-3-on-4-ol ( 7 ) into cyanidin ( 8-B4 ) in the wild-type enzyme and the C13S variant (Extended Data Fig

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J Biol Chem 266: 2140921415

The study observed that the 510 g/day increase of soluble fiber that was accompanied by a 56% decrease in LDL cholesterol was a significant change for PCOS women who, due to their conditioned lifestyle, are at risk of cardiovascular complications like having the heart arteries clogged and impaired blood flow to the heart muscles [131]