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Explore the therapeutic potential of prebiotics, probiotics, and synbiotics as adjunct therapies, educating patients on their role in gut-brain axis modulation and immune support

Ambitious preclinical protocols should aim to reproduce underlying mechanistic hypotheses, not to replicate criticisable clinical designs

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Spermidine , a polyamine found in wheat germ and aged cheese that induces autophagy, and magnesium L-threonate , a magnesium form marketed for crossing into the brain, both rest on small or preliminary trials with no clear cognitive benefit yet

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