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This effect is attributed to PCs dose-dependently enhancing GSK-3 phosphorylation, attenuating caspase-3 activation, and inhibiting lactic acid adhesion protein expression, thereby mitigating oxidative stress and apoptosis induced by AGEs in HUVECs

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Journal of Dental Research, 89 (3), 219-229

2.2.3 Nephroprotective A correlation of improved renal outcomes was demonstrated in a systematic review of 8 RCTs with 39,040 T2DM patients [39]

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