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Skin sensitivity: an emerging signal Skin burning and abnormal touch sensitivity (dysesthesia) appears as a dose-related, reversible signal in two case series and post-market surveillance. Trials did not pre-specify it, and the tirzepatide label does not list it

Virus injection and cannula implantation Mice were deeply anesthetized with pentobarbital (20 mg/kg, i.p.) and were immobilized on a stereotaxic frame (RWD Life Science Inc., China)

Compared with the sham group, there was a significant increase in TG, TC and LDL-C levels and a decrease in HDL-C levels in the DMM group

In the ongoing study of healthy aging, scientists continue to explore novel compounds that may influence metabolism, cellular function, and age-related changes

The peptide shows potential for reducing central sensitization, a key driver of chronic pain