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Pairwise post hoc analysis showed that the SAL/NAL OD group mean withdrawal score (17.2 4.2, n = 10) was significantly greater than the Sham group mean withdrawal score (6.5 0.6, n = 4, p = 0.002)

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252,253 Consistent with these findings, an APAP overdose model revealed that increased GSK-3 phosphorylation contributes to decreased -catenin ubiquitination and proteolysis

4 Oxidative stress in gastric cancer 4.1 Gastric carcinogenesis Under oxidative stress, increased ROS in cells may harm tissues and trigger carcinogenesis, especially in the gastrointestinal system ( Figure 3 )