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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 30% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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On the other hand, SWS deficit has been linked to brain abnormalities, and is often reported in cases of schizophrenia and neurodevelopmental disorder [3]

10.1038/nature07813 Nature 16 ChaudhariA.GuptaR.PatelS.VelingkaarN.KondratovR

Plasma metabolomic signatures in children with autism spectrum disorder and their modulation following a gluten-free modified ketogenic diet