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His performance earned him his first Academy Award nomination, as best supporting actor, and it marked him as one of America's most gifted young actors

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Single-nucleus RNA sequencing analysis revealed that Club cell-specific knockout of Lsm2 leads to a reduction in the Club cell population, particularly those expressing Chia1 + /Crb1 +

It was a small role, but Jimmys presence and line delivery nearly stole the show