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Studies show that E-cigarette use is increasing among middle school and high school students and is the most common form of tobacco use among young adults

For urine samples, a microwave digestion system (Multiwave GO, Anton-Paar, Graz, Austria) was used to digest 5 ml sample with 5 ml HNO 3 and 2 ml H 2 O 2 for 10 min at 100C

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