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doi: 10.1016/j.heliyon.2016.e00130 37 TalamontiEPauterAMAsadiAFischerAWChiurchiVJacobssonA

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Various theories have been posited regarding the pathogenic mechanisms of long COVID, including direct damage to virus-infected tissues (especially the lungs), progressive and continued inflammation due to immune dysregulation, vascular damage and tissue ischaemia caused by increased blood coagulation and subsequent thrombus formation, dysregulation of the renin-angiotensin system caused by viral infection, and post-intensive care syndrome in critically ill patients [ 79 ]