LC-MS/MS showed that CS exposure weakly increased phosphatidylcholine hydroperoxide (PC-OOH)/ phosphatidylcholine (PC) ratios and phosphatidylethanolamine hydroperoxide (PE-OOH)/ phosphatidylethanolamine (PE) in wild type mice, which was markedly enhanced in GPx4+/ mice (Fig
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The primary solvents, PG and VG, act as carriers for nicotine and flavorings, but when exposed to high temperatures, they decompose into reactive carbonyl compounds such as formaldehyde and acrolein, both of which are highly cytotoxic to hepatocytes [120, 121]
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