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Smokers In addition to elucidating the potential role for a nAChR agonist, like nicotine or a manipulated variation of this substance, in the treatment of depression, the researchers also believe that depressed individuals who are smoking may require additional help to quit smoking as a result of its positive effects on their mood

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They can actually be cleaner than roll-ups because they often use oil distillate (no grinder needed!) and you dont have to deal with leftover paper and burnt flower