Our study also found that NRF2, GPX4 and SOD1 expression levels were higher in the neoadjuvant chemotherapy-resistant group compared to the sensitive group, further supporting our hypothesis and demonstrating the adverse effects of GSH on chemotherapy in breast cancer patients
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The link between metabolism and epigenetics cannot be ignored in the relationship between mitochondrial abnormalities and T cell exhaustion, providing important insights for the development of new epigenetic strategies to reverse T cell exhaustion and suggesting that the intrinsic effects of mitochondrial metabolism on T cell functional status should be fully considered when designing therapeutic regimens
Zinc transporters ZnT1 (Slc30a1), Zip8 (Slc39a8), and Zip10 (Slc39a10) in mouse red blood cells are differentially regulated during erythroid development and by dietary zinc deficiency
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