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For females in high-income North America, the upsurge in smoking-attributable mortality was delayed by about 30 years relative to males (Fig

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Firstly, the CHRNB2 associations were based on European ancestry from the UKB (the main rare variant driving the CHRNB2 association occurs only in Europeans) and the CHRNB3 associations were based on Indigenous Mexican ancestry from the MCPS (the main rare variant driving the CHRNB3 association occurs only in Indigenous Mexicans)

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